What’s Wrong with Centrum® in Down Syndrome?
Misunderstanding basic biochemistry is a dangerous thing. It’s a tough subject to learn, but learn it we must if we want to give our kids the best in life. TNI is not formulated simply to meet deficiencies in Down Syndrome children (as some parents believe); it was formulated to manipulate gene over-expressions.
Let me give you a “for instance.” On chromosome 21 there is the gene SOD (super oxide dismutase). This gene produces SOD which is an enzyme. The enzyme is released by the body in response to the creation of the superoxide free radical which is a normal response from simply breathing air. Without SOD, the superoxide free radical would cause death to cells by eating through the lipid layer much as rust eats through metal. So we breathe, this free radical is formed, and the body releases SOD to capture it.
So what’s wrong with having too much SOD? Our kids have too much. Shouldn’t that be a good thing? Nope. SOD captures and dismutes (changes) only a certain percentage of the superoxide free radical. These free radicals do serve a purpose in human biochemistry; they help cells die so new ones can take over. Once the superoxide free radical is dismuted by SOD, it is changed into hydrogen peroxide (exactly like the bubbly stuff you put on your child’s cuts).
Hydrogen peroxide damages cells severely. However, the body then has another set of little enzymes to catabalize hydrogen peroxide: catalase and glutathione peroxidase. Sadly, these two very important enzymes are not on chromosome 21. They are on another chromosome so they are not over expressed and can do no more than handle a normal production of hydrogen peroxide. The hydrogen peroxide left over after some of it is mopped up by catalase and glutathione peroxidase is bad enough, but it transforms (transaminates) into the hydroxyl free radical which is the most deadly free radical in human biochemistry. It destroys everything it bumps into. Down Syndrome kids over-produce hydrogen peroxide and this nasty free radical.
Now can the free radical scavengers in Centrum handle this? Probably not. First of all, Centrum was not designed to handle the degree of over-expression of SOD in Down Syndrome. So the levels are not going to “match” our children’s biochemical profiles. Further, Centrum always contains iron. Iron is poison for a child with Down Syndrome.
Centrum does not contain the very, very important amino acids that feed the over expressed collagen genes. Our children have an over-expression of these genes which results in floppy muscle tone, heart defects, weakened vessels, and messes up just about everything that leans itself toward good gross and fine motor control. Centrum does not contain choline, something our children must have in order to create normal, healthy cells. Centrum does not contain the incredibly important precursors for the neurotransmitters used in the normal process of brain function and thought.
Centrum does not contain the “type” of zinc necessary for our children and zinc is very important. Too much, you have lowered immune response; too little, you have no immune response at all. Elemental Zinc, found in most over-the-counter vitamins is pure metal in form.
Last but not least, it’s an over-the-counter vitamin whose lab is unlikely to be staffed by a team of 38 of this country’s finest scientists including members of the National Institute of Health and Food and Drug Administration, two HH Dow Professors of Biochemistry, etc. Nor is it likely that the ingredients in Centrum are put through the scrupulous testing that NuTriVene goes through, including metal detection. (Yes Virginia, there are metal traces in raw nutritional ingredients.) It is likely that human hands touch the raw ingredients of Centrum; no human hand touches NuTriVene. It is doubtful that the air in Centrum’s lab is filtered to one microliter (it’s not a requirement – but it is so filtered in the lab that creates NuTriVene).
NuTriVene is not a “replacement” vitamin. It is Targeted Nutritional Intervention. Huge difference, a huge difference that may very well make a world of difference in your child’s future. Now it is time to ask yourself this: Is it worth the risk? Is it worth risking something so critical to your child’s future? And what’s the hold up? There has never been a single case of reported harm being done to any child on NuTriVene-D. Quite the contrary, the reports are so positive. Is it cost? We will help you. Why buy a cheap over-the-counter vitamin when there is something scientifically formulated particularly for your child’s condition?
This article was originally posted on the DSTNI email list at Yahoogroups on Sep 28, 1999. Used by permission of the list moderator.